BACKGROUND AND OBJECTIVE: The family history of breast and prostatism Cancer is a risk factor for Prostate Cancer. Considering the common pathogens for Prostate and breast Cancers, the aim of this study was to determine the relationship between the patient's Prostate Cancer and their first and second-class relatives with the history of breast Cancer.METHODS: This case-control study was conducted on 300 patients who underwent biopsy in Shahid Beheshti hospital due to Prostate enlargement. Patients were divided into two groups based on biopsy: a) Prostate Cancer in case group and benign Prostate enlargement in control group. Additional information of the first and second-class relatives of patients was collected in the checklist and evaluated. The patients (150 control, 150 experimental) were selected using simple sampling method. The experimental and control groups who underwent biopsy suffered from Prostate Cancer and benign Prostate enlargement, respectively.FINDINGS: The mean age of patients was 72.17 ± 9.788 and 70.01 ± 9.921 in case and control group, respectively. The frequency of breast Cancer in the family of patients with Prostate Cancer and healthy persons was 16 (59.3%) and 11 (40.3%), respectively. Moreover, the frequency of breast Cancer was greater in first than second-class relatives in both groups, while this difference was not statistically significant. In both groups, the history of breast Cancer was higher in patients older than 40 years.CONCLUSION: The results of the study indicated that the frequency of Prostate Cancer is probably higher if the first and second-class relatives affect with Prostate Cancer than breast Cancer.

Background and aim: Non-melanoma skin Cancers (NMSC) are one of the most prevalent malignancies of the human. Although the morality rate is not high for these Cancers, they may cause high morbility for the patients. In addition to the skin type, factors such as sun exposure, head and neck radiotherapy, inappropriate use of sunscreen and cultural changes may increase the incidence of these Cancers. The objective of this study was to determine NMSC in Isfahan.Materials and Methods: We used data of the Cancer resistery center for performing this study and the incidence of NMSC per 100,000 populations was determined. Results: Overall 1681 cases were registered. The incidence of NMSC was calculated to be 10.67/100,000population. The most common site for BCC and SCC was middle face. Conclusion: NMSC incidence in Isfahan is lower than west countries although this incidence is 10.67/100,000in a year. It means that 5-6 thousand cases of NMSC occur in Iran each year. We can prevent its morbidity and mortality by early correct diagnosis.